Replace an EPUB's cover image, or add one where it is missing - here in this tab, with nothing uploaded.
Changing a cover should not mean uploading your book. The EPUB is opened, given its new cover and saved again, all in your browser.
About 1600 × 2560 pixels (a 1:1.6 ratio) suits most readers and stores. Any size works; JPEG or PNG.
E-readers cache covers. Delete the book from the device and copy the new file across, or re-import it in Calibre or Apple Books.
No - only the cover image and the entries that point to it. Text, styles and metadata stay as they were.
Only if they have no DRM. Copy-protected books are encrypted, and removing that is not something this site does. Books from Project Gutenberg, Standard Ebooks, Humble Bundle and most indie stores are DRM-free.